Genetix laboratory offer a complete range of molecular biology contract research services designed to support your research programs, in compliance with international standards. We will execute specific research projects and deliver the results at your doorstep with the help of best talent available to solve any given problem. With a strong scientific and technical advisory board, we work closely with your research investigator to design and customize according to your specific study needs. All projects will be professionally and confidentiality maintained for your reference. Our services range from nucleic acid extractions to a complete setup of your research laboratory.

Genomics DNA Purification:

• Nucleic acid extractions followed by normalization, aliquoting and plating: DNA/RNA extraction and plasmid extractions from variety of samples.
• We offer cost-effective High through Put and High Molecular Weight DNA extraction from plants and animal tissues.
• We offer purification of high molecular weight DNA from different tissues (rich in secondary metabolites and polyphenolic compounds) of various plants and animals.
• Plants: Corn, Soybean, Cotton, Tomato, Sunflower, etc. Different tissues - seeds, leaves, roots, etc. Plasmid DNA Purification: We also offer small and large scale isolation of plasmid and BAC DNA, suitable for Southern Blotting, PCR and genotyping.
• Whole genome amplification from very low amount of samples (starting from 10ng DNA)

Qualitative PCR and Quantitative Real Time PCR:

• Qualitative PCR testing for customized assays for detection of cytogenetic abnormalities and localization of specific DNA in clinical and research based samples. PCR & PCR product purification along with different PCR modification services is being offered by us.
  
  
• Quantitative Real time PCR testing services to meet preclinical and clinical requirement and application of Real-Time and end-point PCR for high throughput gene expression analysis and genotyping. QPCR services are built upon a state-of-the-art technology platform. Our QPCR system detects and quantitates nucleic acid sequences in a high-throughput mode suitable for the requirements of today's drug discovery process. Using these systems we can accommodate any real-time QPCR need with standard or customized SYBR Green & TaqMan assays. We offer:
  
  
  1. Residual DNA testing
  2. Biodistribution studies
  3. Genetic stability testing
  4. Custom QPCR assay development
  5. Custom QPCR assay validation
  6. Gene Expressions & Quantification related studies
  7. Research and Regulated services
  8. Customized assay development relevant for diagnosis of diseases and Tumor/ cancer Marker detection by Real Time-PCR
  9. High throughput capacity
  10. SNPs, VNTRs and STR techniques for genotyping and forensics with the option of customized genome analysis.

Cloning services:

We clone genes in the vector of your choice. Gene optimization is done to achieve higher productivity and stability in the host. We also synthesize genes using sequence information provided by the customer and clone into one of our standard vectors - pUC based vectors or TA vectors. We then sequence both strands of the gene. We provide the following to the customer:

• Plasmid DNA
• Glycerol Culture
• Transformation
• Sequence of the gene
• Production of cDNA libraries either from extracted RNA or directly from clinical samples.
• High throughput cloning and expression analysis of recombinant proteins and Screening of crystallization conditions for purified proteins.
• Gene knockdown by RNAi and validation by Real Time PCR or western blot analysis

Computational Genomics:

Comparative genomics involves the comparison of genomes where similarity between the genomes of two organisms is determined to gain additional insights about the composition of genomes and regions of similarity.

It also can be helpful in knowing:

• Compare DNA and protein sequences to public and internal databases
• Align multiple sequences and analyze gene evolutionary relationships
• Determine DNA and protein motifs
• Select PCR primers
• Assemble sequencing fragments
• Construct vectors

Lab set up consultancy services:

Consultancy for setting up new molecular biology laboratories and accept turn key projects for new set ups both in terms of contract research services and supply of instruments and chemical and reagent supplies.